It will also come to pass that before they call, I will answer; and while they are still speaking, I will hear. (Isaiah 65:24)

Before they call . . . while they are yet speaking. Relationship with the Lord will be so close that he will anticipate and provide for every need. (John MacArthur)

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God will anticipate their prayers with the blessings of his goodness. David did but say, I will confess, and God forgave,Psa 32:5. The father of the prodigal met him in his return. While they are yet speaking, before they have finished their prayer, I will give them the thing they pray for, or the assurances and earnests of it. These are high expressions of God’s readiness to hear prayer; and this appears much more in the grace of the gospel than it did under the law; we owe the comfort of it to the mediation of Christ as our advocate with the Father and are obliged in gratitude to give a ready ear to God’s calls. (Matthew Henry)